On The Table Read Magazine, “the best entertainment eBook magazine UK“, Alzheimer’s: Prevention Is The Cure by Patrick Holford reveals how 99% of people can prevent Alzheimer’s through diet, lifestyle, and environmental changes, offering a science-backed roadmap to protect your brain and reduce dementia risk by up to 80%.

Alzheimer’s: Prevention Is The Cure
A groundbreaking new book, Alzheimer’s: Prevention is the Cure, challenges the long-held belief that Alzheimer’s disease is an inevitable part of aging. Authored by Patrick Holford, Chair of the Alzheimer’s Prevention Expert Group and founder of the charity Food for the Brain, the book asserts that less than 1% of Alzheimer’s cases are caused by genetics, meaning prevention is within reach for the vast majority. Backed by a global initiative and extensive research, the book offers a science-based roadmap to reduce dementia risk by up to 80% through diet, lifestyle, and environmental adjustments.

Holford and his team, including neurologist Dr. David Perlmutter, argue that Alzheimer’s is not primarily a genetic disease but the result of a “perfect storm” of modifiable factors that impair brain structure, function, or energy supply. Unlike mainstream approaches that focus on amyloid plaques and p-tau proteins—targets of largely ineffective drugs—the book emphasizes lifestyle-driven prevention. “Alzheimer’s is not caused by one thing, but a combination of factors unique to each person,” Holford explains, dismissing the idea of a single pharmaceutical solution.

The Food for the Brain Foundation has tested over 400,000 people using a free online Cognitive Function Test, which assesses dementia risk and provides personalized diet and lifestyle recommendations. Users can track their progress over time with a Dementia Risk Index score. Alarmingly, cognitive decline can begin as early as age 18, with noticeable impairment often appearing by the 70s or 80s. The good news? Holford insists that decline can be halted—and even reversed—with the right interventions.
The Four Horsemen of Brain Health
Central to the book’s message are four key dietary risk factors, dubbed “the four horsemen of the brain health apocalypse”:
- Insufficient omega-3 fats: Increasing omega-3 intake through fish or supplements can reduce dementia risk by 20%. Most people fall below the recommended omega-3 index of 8%, with levels under 5% linked to brain shrinkage and higher dementia risk.
- Low B vitamins: Elevated homocysteine, a harmful amino acid tied to low B vitamin levels, is a major risk factor. Supplementing with B vitamins can lower homocysteine and cut dementia risk by up to a third.
- Inadequate antioxidants: Diets rich in antioxidant-packed fruits, vegetables, and vitamin C can halve the risk of cognitive decline, as shown in a study of 2,716 people over 60.
- Excess sugar and refined carbs: Reducing sugar and processed foods can lower Alzheimer’s risk by 20%.

Optimizing vitamin D levels also plays a critical role, with supplementation linked to a one-third reduction in dementia risk. Research from the Netherlands reinforces this, showing that low levels of omega-3, B vitamins, and vitamin D increase dementia risk fourfold.

Beyond Diet: A Holistic Approach
The book goes beyond nutrition, highlighting lifestyle factors that protect brain health:
- Exercise: Regular physical activity supports cognitive function.
- Social engagement: Staying connected reduces risk.
- Sleep and stress management: Quality sleep and stress reduction are vital.
- Sensory health: Addressing hearing and vision issues is key.
- Hormonal balance: For women, managing menopause-related changes, including natural hormone replacement therapy, can lower risk.
The Economic and Personal Impact
The book’s prevention model isn’t just about personal health—it could save billions. Dr. Apostolos Tsiachristas, Associate Professor in Health Economics at Oxford University, estimates that B vitamin supplementation to reduce homocysteine could save the UK £60 million annually and extend life expectancy by 14 years. Yet, mainstream healthcare has been slow to adopt these strategies. Food for the Brain now offers a home test kit to measure critical markers like homocysteine, vitamin D, omega-3, blood sugar, and antioxidant status—most of which are rarely tested by GPs.
Find more from Patrick Holford now:
Kindle: https://amzn.to/4jtVx4A
Audible: https://amzn.to/4jkxAMY
Apple Audiobook: https://apple.co/4k7Q0S5
To take the test yourself visit www.foodforthebrain.org
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